Mahonia Aquifolium – also known as Oregon Grape Root or Berberis Aquifolium

Oregon-Grape-root-Mahonia-aquifolium-Berberis-aquifolium

Mahonia Aquifolium- also known as Oregon Grape Root or Berberis Aquifolium

 Botanical Names are Berberis aquifolium and Mahonia aquifolium

Its properties are antiproliferative, antimicrobic, antimutagenic and antioxidant

The berries are edible and are rich in vitamin C but it is the root of the plant that is used for its medicinal properties.

The plant contains alkaloids berberine, berbamine, canadine, and hydrastine.  It is believed that these alkaloids inhibit the ability of bacteria to attach to human cells and so prevent the spread of infection.

Oregon Grape root is used for for the natural treatment of atopic dermatitis, psoriasis, eczema and seborrhea (scalp psoriasis).

The roots of mahonia aquifolium contain isoquinoline alkaloids, which include jatrorrhizine, berberine, palmatine, magnaflora and columbine.  It is considered that these alkaloids are active plants components that have anti-microbial and antifungal effects.

Alkaloids berberine, jatrorrhizine, and magnoflorine are antioxidant.

Oregon grape (Mahonia/ Berberis aquifolium) extract was found to inhibit the growth of keratinocytes by 50% in vitro. This is useful to manage psoriasis as people with psoriasis have a faster than normal turnover of skin cells in the top layer of the skin.

Laboratory tests have shown that Oregon grape can kill or suppress the growth of candida and other fungal infections, staphylococcus, streptococcus, E. coli, Entamoeba histolytica, Trichomonas vaginalis, Giardia lamblia, Vibrio cholerae, and other harmful microbes.

One of the primary actions of this herb is an improvement of blood flow to the liver.  It also stimulates intestinal secretions and bile flow.

Traditionally, a tincture of the herb has been used, orally and topically, to treat eczema, acne, conjunctivitis and herpes.

Additional historical and traditional uses include the treatment of gall bladder disease, hemorrhages and a few forms of cancer.

Animal studies have indicated that it may enhance the performance of some antibiotics but no clinical trials have as yet been carried .

Read about M-Folia studies and clinical trials

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Psoriasis – differences between men and women

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Psoriasis – Differences Between Men and Women

Do men suffer from more severe psoriasis than women?
 
A recent Swedish study of 5,438 patients with moderate to severe psoriasis found that "women had statistically significantly lower median PASI scores (5.4) than men (7.3), consistent across all ages.
 
The authors concluded:
"For more than 70 years it has been speculated that women have less severe psoriasis compared with men. By investigating, for the first time, the sex differences in the severity of psoriasis using the gold standard of severity measurement—the PASI score—and the distinct elements of the PASI score, we were able to corroborate this thesis in a nationwide population. Further research is needed to substantiate this finding in different populations."
 

Hägg, D., Sundström, A., Eriksson, M. et al. Am J Clin Dermatol (2017). doi:10.1007/s40257-017-0274-0
 

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